Séverine Chaumont-Dubel Selected Research

serotonin 6 receptor

1/2023	Impact of 5-HT6 Receptor Subcellular Localization on Its Signaling and Its Pathophysiological Roles.
1/2023	Spatiotemporal dynamics of 5-HT6 receptor ciliary localization during mouse brain development.
9/2022	Early 5-HT6 receptor blockade prevents symptom onset in a model of adolescent cannabis abuse.
1/2021	Structure-Based Design and Optimization of FPPQ, a Dual-Acting 5-HT3 and 5-HT6 Receptor Antagonist with Antipsychotic and Procognitive Properties.
10/2020	mTOR activation by constitutively active serotonin6 receptors as new paradigm in neuropathic pain and its treatment.
1/2020	The 5-HT6 receptor interactome: New insight in receptor signaling and its impact on brain physiology and pathologies.
1/2020	Early 5-HT6 receptor blockade prevents symptom onset in a model of adolescent cannabis abuse.
10/2012	5-HT(6) receptor recruitment of mTOR as a mechanism for perturbed cognition in schizophrenia.

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Séverine Chaumont-Dubel Research Topics

Disease

4	Neurobehavioral Manifestations 01/2023 - 01/2020
4	Mental Disorders (Mental Disorder) 01/2023 - 01/2018
4	Schizophrenia (Dementia Praecox) 01/2023 - 10/2012
3	Cognitive Dysfunction 01/2023 - 10/2012
3	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2023 - 01/2021
2	Marijuana Abuse (Cannabis Abuse) 09/2022 - 01/2020
2	Memory Disorders (Memory Loss) 01/2021 - 01/2018
1	Autism Spectrum Disorder 01/2023
1	Frontotemporal Dementia (Semantic Dementia) 01/2021
1	Tauopathies 01/2021
1	Hyperalgesia 10/2020
1	Neuralgia (Stump Neuralgia) 10/2020
1	Peripheral Nervous System Diseases (PNS Diseases) 10/2020
1	Neoplasms (Cancer) 01/2020
1	Glioblastoma (Glioblastoma Multiforme) 01/2020
1	Inborn Genetic Diseases (Disease, Hereditary) 10/2016
1	Neurofibromatosis 1 (Neurofibromatosis Type I) 10/2016
1	Nervous System Neoplasms (Neoplasms, Nervous System) 10/2016
1	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 10/2013
1	Disease Progression 10/2013

Drug/Important Bio-Agent (IBA)

8	serotonin 6 receptorIBA 01/2023 - 10/2012
2	Serotonin (5 Hydroxytryptamine)IBA 01/2023 - 11/2020
2	Phencyclidine (Angel Dust)IBA 01/2018 - 10/2012
2	Proteins (Proteins, Gene)FDA Link 10/2016 - 10/2013
1	LigandsIBA 12/2022
1	Serotonin ReceptorsIBA 01/2021
1	5-HT3 Serotonin Receptors (5 HT3 Receptor)IBA 01/2021
1	Ondansetron (Zofran)FDA LinkGeneric 01/2021
1	serotonin 7 receptorIBA 01/2021
1	tau Proteins (tau Protein)IBA 01/2021
1	Oxaliplatin (Eloxatin)FDA LinkGeneric 10/2020
1	Analgesics (Analgesic Drugs)IBA 10/2020
1	Cell-Penetrating PeptidesIBA 10/2020
1	Dronabinol (THC)FDA LinkGeneric 01/2020
1	Connexin 43 (Connexin43)IBA 01/2020
1	Chemokine ReceptorsIBA 01/2020
1	Nootropic Agents (Nootropics)IBA 01/2018
1	Scopolamine (Hyoscine)FDA Link 01/2018
1	compound 17IBA 01/2018
1	Donepezil (Aricept)FDA LinkGeneric 01/2018
1	Neurofibromin 1 (Neurofibromin)IBA 10/2016
1	angiogeninIBA 10/2013
1	Antipsychotic Agents (Antipsychotics)IBA 10/2012
1	Sirolimus (Rapamycin)FDA Link 10/2012

Therapy/Procedure

1	Secondary Prevention 01/2020